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Category: q-bio.GN

  • Scalable Single-Cell Gene Expression Generation with Latent Diffusion Models

    Scalable Single-Cell Gene Expression Generation with Latent Diffusion Models arXiv:2511.02986v1 Announce Type: new Abstract: Computational modeling of single-cell gene expression is crucial for understanding cellular processes, but generating realistic expression profiles remains a major challenge. This difficulty arises from the count nature of gene expression data and complex latent dependencies among genes. Existing generative models…

  • CN-SBM: Categorical Block Modelling For Primary and Residual Copy Number Variation

    CN-SBM: Categorical Block Modelling For Primary and Residual Copy Number Variation arXiv:2506.22963v1 Announce Type: new Abstract: Cancer is a genetic disorder whose clonal evolution can be monitored by tracking noisy genome-wide copy number variants. We introduce the Copy Number Stochastic Block Model (CN-SBM), a probabilistic framework that jointly clusters samples and genomic regions based on…