STAT+: Scientists show that mRNA therapy can be delivered as a capsule
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An oral capsule can efficiently deliver liquid mRNA therapy directly to the gut, a possible new delivery mechanism for mRNA vaccines, a new study finds.<\/p>\n
In the study published in Science Translational Medicine<\/a> on Wednesday, researchers said they successfully used RNACap, a capsule engineered to prevent stomach acids from degrading liquid mRNA therapy to treat inflammatory bowel disease. Once the capsule was in the gut, they used normal stomach contractions to release the mRNA therapy.\u00a0<\/p>\n \u201cThis shows the massive appetite and potential for delivery of mRNA therapeutics,\u201d said Jacob Becraft, CEO of Strand Therapeutics, an early-stage biotech developing new mRNA therapies. \u201cOral delivery would be a huge win for delivery to the GI.\u201d Becraft was not involved in the study.<\/p>\n Continue to STAT+ to read the full story\u2026<\/a><\/p>\n<\/div>\n